PROACTIVE

The PROACTIVE project aims to develop a high throughput multiplexed protein detection technology for blood-based biomarkers, using a custom-designed collaborative Web-LIMS with integrated algorithms and exclusive scientific visualizations produced by Integromics.
It is a cooperation initiative funded by the VII Framework Program of EU were the partners are Olink AB (Sweden), Innova Biosciences (UK), Uppsala University Hospital (Sweden), University of Copenhagen (Denmark), Fujirebio Diagnostics AB (Sweden) and Integromics (Spain). Proactive´s major aim is to develop a validated and fully operational high throughput technology to detect large sets of putative cancer protein-biomarkers in human blood samples, the development of data management and analysis software tools and the validation of the detection technology using patient samples with and without colorectal cancer. Integromics’ major contribution is the development of software tools for data analysis and management.


RESOLVE

The RESOLVE project is intended to provide researchers and clinicians with data on genes involved in ageing, wound healing and fibrosis, and relies on Integromics solutions for collaborative Web-LIMS custom design and implementation, and advanced bioinformatics data mining.
It is a cooperation initiative funded by the VII Framework Program of EU were some of the partners are, Medical University of Vienna (Austria), University of Verona (Italy), Biotalentum Ltd (Hungary), National Center of Biotechnology (Spain), Bristol University (UK), Catholic University of Louvain (Belgium) y el Technological Institute of Austria (Austria). Resolve’s major objective is to identify and characterize validated molecular targets capable of shifting primary organ repair towards fibroproliferative wound healing (major pathology) as a result of an age-dependent loss of regulatory control capacities.
Integromics’ major contribution is the development of the bioinformatics platform for the project results and the functional bioinformatics analysis of putative molecular targets.


LipidomicNet

LipidomicNet is a project aimed at creating a knowledge base for the study of lipids using proteomics, microarrays and qPCR technologies.
It is a cooperation initiative funded by the VII Framework Program of EU, in close collaboration with LIPID MAPS and Lipid Bank – Japan, were some of the partners are Regensburg University (Germany), Utrecht University (Holland), Bonn University (Germany), París University (France), Max-Planck Institute (Germany), European Bioinformatics Institute (UK), Biobase Gmbh (Germany). LipidomicsNet’s major aim is to establish high-throughput methods to define drugable targets and novel biomarkers related to lipid and protein species of lipid droplets (involved in energy overload diseases), their interactions and regulation mechanisms. Integromics’ major contribution is the development of Integromics’ custom LipiMiner for qPCR data analysis and data integration that consists in a Wiki formatted bioinformatics platform that will be integrated in existing lipidomics’ platforms.


ProteomeXchange

ProteomeXchange is a cooperation initiative funded by the VII Framework Program of EU (coordination and support action) were the coordinator is the European Bioinformatics Institute (EBI) (UK) and the partners are the University of Liverpool (UK), VIB (Belgium), ETH (Zurich), ISB (USA), University of Michigan (USA), RUB (Germany), SIB (Switzerland), GeneBio (Switzerland), Wiley-VCH (Germany) and CSIC (Spain). ProteomeXchange’s aims to develop and implement standards for proteomics data representation, management and exchange between the major proteomics data repositories. Integromics participates contributing to the standards definition and by implementing the new proteomics standards in OmicsHub®, its commercial proteomics data management system.


IRIS
The goal of the project is to develop an integrated environment for the analysis of high content screening data with the RealTime StatMiner® bioinformatics software for RT-qPCR validation.
It is a cooperation initiative promoted by the EraNet EuroTransBio and funded by each partner national/regional bodies. Integromics as coordinator collaborates in this project with CENIX BioScience. IRIS project aims at developing an integrated analysis environment for high throughput analysis of gene expression data and the associated phenotype coming from high-throughput interference RNA (RNAi) experiments. This type of analysis is essential for the pharmaceutical and biotechnology industry for the discovery of novel therapeutic targets.

Apliclinics
It is a public-private collaborative Project funded by the Spanish Ministry of Economics and Competitiveness through the INNPACTO program and by the European Fund for Regional Development. Integromics collaborates with the Galician foundation of Genomics Medicine. ApliClinics’ aims to develop tools for high throughput data analysis in the field of clinical genomics, to overcome the actual limitations, both at the experimental and bioinformatics levels, confronted by the clinical laboratories that aim to use Next Generation Sequencing (NGS) technology.
AMIT

AMIT is a public-private collaborative Project funded by the Spanish Ministry of Economics and Competitiveness through the CENIT program and by the European Fund for Regional Development were are participation several enterprises and public centers with high relevance in the national and international spheres. AMIT’s aims to develop new technology to improve the current molecular imaging techniques in medicine and biomedicine. Integromics’ main contribution is the implementation of bioinformatic tools for the analysis and management of the molecular information associated to the bio/medical images.

